Pharmacology - Alexandria Faculty of Medicine

عن القسم
أنشطة
سمات التميز
الامكانات و الموارد المتاحة

رؤية القسم

رسالة القسم

أهداف القسم الأستراتيجية 2021 الى 2026

رؤية القسم

رسالة القسم

أهداف القسم الأستراتيجية 2021 الى 2026

Confrences

Publications

Workshops

Training

Confrences

مؤتمرات	date	palce held
Challenging virus C in Egypt ” Dreams versus reality”	25/5/2017	Convention center faculty of medicine alexandria university
New trends in cardiovascular pharmacology	29/3/2018	Convention center faculty of medicine alexandria university
Save your kidney	Mar-23	Convention center faculty of medicine alexandria university
Cardio-alex	2022	alexandria bibliothek
Pediatric Asthma and Allergy Meeting PAAM, Florence	2018
World Kidney day 2023	2023
American Association of Clinical Endocrinologists (AACE) Middle East North Africa conference	19/11/2023	Dubai,UAE

Publications

Staff Member	Publications
Hassam Mohamed Ali Sakr	Study of the effect of somatostatin analogue; octreotide acetate (SMS = SANDOSTATIN 201-995), portal-induced acute hypertension in dogs Alexandria Medical Journal, Vol. 33, no 3-4,1991
Sami Hussein Mahmoud Hamadi	sPropranolol withdrawal and thyroid functions in the rabbit. Bull Alex Fac Med, Vol 27, No 5, 1991. 2- Possible alteration of some cardiovascular and hormonal parameters after abrupt withdrawal of propranolol or guanfacine following chronic mono or combined therapy in SHR. Bull Alex Fac Med, Vol 27, No 5, 1991. 3- Study of the cardioprotective effects of pinacidil, propranolol, atenolol, nimodipine and nitrendipine against isoproterenol induced myocardial infarction. J Egypt Soc Pharmacol Exp Ther, Vol 10, No 3, 1991. 4- Correlation between changes of thyroid function and serum lipid profile induced by nadolol and pindolol in the rabbit. J Med Res Instit, Vol 13, No 4, 1992 5- Hepatic effects of hallothane and isoflurane anaesthesia in rats and their relation to enzyme induction.Bull Alex Fac Med, Vol 28, No 3, 1992 6- Modification of the antinociceptive effect of morphine, meperidine and diclofenac by thiopentone sodium and diazepam in rats. Tanta Medical J, Vol 20, No 30, 1992. 7- Effect of propranolol and bisoprolol administration and withdrawal on blood pressure, heart rate, urinary catecholamines and thyroid hormones in SHR. J Egypt Soc End Met Diab, Vol 24, No 2, 1992. 8- Study of the antisecretory and cytoprotective effects of different doses of cimetidine on induced gastric ulcer by sodium taurocholoate in rats. Accepted for publication in J Egypt Soc Pharmacol Exp Ther, on 15/3/1992. 9- Study of the potential hepatoprotective effect of histaminergic receptor blockers (H2 – blockers) on the drug induced hepatic insult in the rabbit. Accepted for publication in J Med Res Instit, on 4/7/1992. 10- Effects of nifedipine, nimodipine, verapamil, diltiazem and propranolol in aminophylline induced arrhythmia in dogs. Accepted for publication in J Egypt Soc Pharmacol Exp Ther, on 27/5/1993. 11- Effects of captopril administration and withdrawal on some cardiovascular, hormonal and biochemical parameters in hypertensive patients and normal rats. Accepted for publication in J Egypt Soc Pharmacol Exp Ther, on 3/9/1993. 12- Alterations in bile dynamics and bile composition by calcium entry blockers in dogs. Accepted for publication in J Egypt Soc Pharmacol Exp Ther, on 10/9/1993. 13- The possible hepatic and renal toxic effects of some non-steroidal anti- inflammatory drugs. J Egypt Soc Pharmacol Exp Ther, Vol 12, No 1, 1993. 14- Interaction between maprotiline and contraceptive pills on brain amines and some hormonal parameters in rats. J Egypt Soc Pharmacol Exp Ther, Vol 12, No 1, 1993. 15- Role of thyroxin in protection against gentamicine induced nephrotoxicity in rats. J Egypt Soc Pharmacol Exp Ther, Vol 12, No 1, 1993. 16- Study of the role of benzodiazepines in hepatic encephalopathy.Bull Alex Fac Med, Vol 29, No 2, 1993.
Safaa Hussein Mohamoud ElRowany	• Safaa H.ELRewini& co-authors (1997).Effect of indomethacin and tenoxicam alone and as adjuvant to praziquantel on granulomatus reaction in experimental Schistosomiasis: :involvement of endogenous histamine . The New Egyptian Journal of Medicine Vol16 No.1, • Safaa H.EL-Rewini& co-authors (1998). Pinacidil-induced epithelium dependent relaxation of guinea-pig isolated trachialis:Its antagonism by guanithedine,glibenclamide and phentollamine. The New Egyptian Journal of Medicine Vol 18, No 5 • Safaa H.ELRewini& co-authors (1996).Effect of potassium channel modulators on histamine release from rat peritoneal mast cells . The New Egyptian Journal of Medicine Vol 14, No 4 • Safaa H. El-Rewini,& co-authors (1997). A study of the effect of H1and H2-receptor blocking drugs on the normal healing process of the excised skin wound in the rat. Bull Alex Fac Med Vol XXXIII, No 2. • Safaa H. El-Rewini,& co-authors (1997). Effect of the calcium channel blocker “felodipine” on single oral and intravenous theophylline dose kinetics in the rabbit. Bull Alex Fac Med Vol XXXIII, No 3. • Safaa H. El-Rewini,& co-authors (1998).Astudy of the possible prophylactic effects of vitamin A,,vitamine C and zinc sulphate on some bone changes in overiectomised rats. Bull Alex Fac Med Vol XXXIV, No 2. • Safaa H. El-Rewini& co-authors (1999)..Effect of carbamazepine and valproate on optical bone density in epileptic children. Alex Journal of Paediatrics Vol 13 No1. • Safaa H. El-Rewini& co-authors (1999)..Effect of carbamazepine and valproate on thyroid function in epileptic children. Alex Journal of Paediatrics Vol 13 No1. • Safaa H.El-Rewini& co-authors (1998).Effect of raloxifane on some bone changes serum cholesterol and uterine weight in ovariectomized. The New Egyptian Journal of Medicine Vol19 No.3, • Safaa H.El-Rewini& co-authors (1995).Synthesis of novel estradiol thiosemicarbazone derivative as potential antiestrogens.Alex journal of pharmaceutical science Vol 9 No2 • Safaa H.El-Rewini& co-authors (1996). . Novel steroidal 1,4-diketones and pyridazine derivatives as potential antiestrogens. Arch Pharm Pharm Med Chem Vol 329. • Safaa H.El-Rewini& co-authors (2oo2). Evaluation of the effect of some drugs modulating the level of intercellularadhesive molecule-1 on hepatic fiberosis in experimental shistosomiasis. Bull Alex Fac Med Vol 37, No 2. • Safaa H.El-Rewini& co-authors (2004)…Astudy of cytoprotective effect of clarithromycine on the induced gastric mucosal injury in rat . Bull Alex Fac Med Vol 40, No 4. • Safaa H.El-Rewini& co-authors (2005)). Effect of folic acid and vitamin B12 supplementation on isoprenaline induced M I ,endothelial function and atherothrombosis in experimental hyper homocysenemic rats. Bull Alex Fac Med Vol 41, No 1.. • Safaa H.El-Rewini& co-authors (2004). Comparative study of protective role of nigella sativa oil ,esteradiol and alendronates on steroid induced osteoporosis in rat. Bull Alex Fac Med, Vol 40, No3. • Safaa H.El-Rewini& co-authors (2003). Study of the mechanism underlying the prokinetik action of erythromycin on lower oesophageal sphincter pressure in dogs. Alex Med Journal Vol 45 No 1 . • Safaa H.El-Rewini& co-authors (2003). Comparative study of the effect of peroxisome proliferation activated receptor gamma ligands and ACE inhibitors on experimental colitis in rats.Journal of the Med Research Institute Vol 24 No 3, • Safaa H.El-Rewini& co-authors (2005).Protection against acute adriamycin induced cardiotoxicity by nigella sativa oil ,thymoquinone,garlic extract and COQ10 in rat Bull Alex Fac Med, Vol 41, No1. • Safaa H.El-Rewini& co-authors (2004)..Invitro study on the effect of histamine H2 receptor antagonism on neuromuscular transmission. The New Egyptian Journal of Medicine Vol 31, No 2. • Safaa H.El-Rewini& co-authors (2004).Effect of vitamin E and melatonin on blood level of matrix metalloproteinase-9 and some hepatic antioxidants in an experimental model of hepatocelluler injury. Journal of the Med Research Institute Vol 25 No 2., • Nesrine S. El-Mezayen, Rehab A. Abd el Moneim, Safaa H. El-Rewini. Vitamin B12 as a Cholinergic System Modulator and Blood Brain Barrier Integrity Restorer in Alzheimer’s Disease. European Journal of Pharmaceutical Sciences 2022(ISI Impact factor 4.38) Volume 174, issue106201 • Effect of combined therapy with Rosuvastatin and Memantine on TGF-β1/Smad Signaling Pathway in Experimental model of Alzheimer’s disease in rats. Poster at3rd PUA International Conference “Innovation in Pharmaceutical Sciences Inflammopharmacology https://doi.org/10.1007/s10787-023-01376-w Inflammopharmacology ORIGINAL ARTICLE L‐Carnitine augments probenecid anti‐inflammatory effect in monoiodoacetate‐induced knee osteoarthritis in rats: involvement of miRNA‐373/P2X7/NLRP3/NF‐κB milieu Rawan Mahfouz1 · Safaa H. El‐Rewini1,2 · Asser I. Ghoneim3 · Eman Sheta4 · Mennatallah A. Ali1 · Sherihan Salaheldin Abdelhamid Ibrahim1 Received: 25 May 2023 / Accepted: 13 October 2023 © The Author(s) 2023
Madeiha AbdelHalim Hassan Ali	1. M. El-Dakhakhny, M. Barakate, M. Abd El-Halim, S.M. Aly. Effects of Nigella Sativa Oil On Gastric Secretion And Ethanol Induced Ulcer In Rats. Journal of Ethnopharmacology 72; 2000 2. Mohamed El-Dakhakhny, Naglaa I. Mady, Madiha Abdel Halim. Nigella Sativa Oil Protects Against Induced Hepatotoxicity And Improves Serum Lipid Profile In Rats. Arzneimittel Forschung-Drug Research 50 (II), No.9 (2000) 3. M. El-Dakhakhny, M. Abd El-Halim, T. Abd El-Aziem, I. El-Said Darwish. Inhibition Of Tumor Necrosis Factor- And Nitric Oxide Synthase Has A Hepatoprotective Effects In Carbon Tetrachloride- Induced Liver Injury In Rats. Egypt. Soc. Pharmacol. Exp. Ther., vol.20, No.1, 2001 4. Mohamed I. El-Dakhakhny, Tarek Abdel Aziem, Madiha Abdel Halim. The Influence of Erythromycin, Roxithromycin, Azithromycin, Clarithromycin And Nigella Sativa Oil On Bleomycin-Induced Acute Lung Injury In Rats. Naunyn-Schmiedeberg’s Archives Of Pharmacology Supplement to vol.364(3); September 2001 Page R25 Abstracts of the Joint Meeting of The Swiss Society of Pharmacology & Toxicology, The German Society For experimental and Clinical Pharmacology & Toxicology and The Austrian Pharmacology Society. 5. Mohamed I. El-Dakhakhny, Madiha A. El-Halim, Samia M. Aly, Mervat K. Barakat, Nahed I Zohdy. Protective Effect of Nigella Sativa Oil And Clindamycin Against Production Of Tumor Necrosis Factor- And Liver Injury In Murine Septic Peritonitis. A Pharmacological and Histological Study. Egypt. Soc. Pharmacol. Exp. Ther., vol.19, No.2, 2000 6. Nayel O.A. Hassan I.E., El-Halim M.A. Youssif M.I. Striking By Metabolic Modulation To Protect Against Intestinal Ischemic-Reperfusion Injury In Rats By Different agents. Proceedings Of The 15th Annual Conference For The Egyptian Society Of Toxicology. 6-7 October 1999; Vol. One 7. Nabil El-Halawani, Nahla A.M. Hamed, Madiha A. El-Halim. Use of Antioxidant As Adjuvant Therapy In Leukemic Patients. Alex. Med. J 1999; 41(3) 8. Madiha A. El-Halim and Hoda M. Khalifa. Pharmcological and Histological Evaluation of The Gastroprotective Effects Of Some Drugs In Rats. Role of Antioxidant Mechanisms. Bull. Alex. Fac. Med. Vol.35 No.3, 1999 9. Omnia A. Nayel, Madiha A. El-Halim, Magid M. Matta, Magda I. Youssif. Probing in The Modulation of Myocardial Ischemic-reperfusion Injury in A Rat Model by Different Agents”. Bull. Alex. Fac. Med. Vol.33 No.3 1997 10 Nahla A. M. Hamed, Madiha Abdel Halim, Nadia A. Abdel- Moneim. Oxidative Stress As A possible Mechanism of Resistance to Anthracycline-Based Regimens in Acute Leukemia: Role Histamine in Radical Release. The 46th Annual Conference of Egyptian Society of Pharmacology and Experimental Therapeutics. April 2003. 11. Nahla A.M. Hamed, Madiha A. Halim, Alaa Abdo, Abdel Salam Ateia. Involvement of caspase-3, iron regulatory protein-1 and nitric oxide synthase in the antimetabolite chemotherapy mediated response in nitric oxide sensitive versus resistant malignancies. Med. J. Cairo Univ. 2004; 72(4) Suppl. 167-80. 12. Mohamed T. Ghoneim, Nagwa M. Nour El Din, Madiha A. El-Halim, Aida A. Guemei. Study of Possible Effects of Hormonal Therapy on Experimentally Induced Colitis In Rats. Bull. Alex. Fac. Med. 2004; 40(1): 57-64. 13. Samia M. Ali, Mohamed I. El-Dakhakhny, Tarek Abd El-Azim, Madiha A. El-Halim. Effect of Trandolapril, Candesartan and Nigella Sativa Oil on Insulin Resistance In Diabetic Rats. J. Egypt. Soc. Pharmacol. Exp. Ther. 2005; 26(2): 517-48. 14. M. El-Dakhakhny, M.A. H. Hassan, M.M. Matta. Relative Contribution of Transient Receptor Potential Channel (TRPC) and Dihydropyridine-sensitive Calcium Influx To Contractile Response Of α-Adrenergic Agonists In Rat Aortic Strips. JMRI 2005; 26(3): 237-42. 15. El-Dakhakhny M., Abd El-Azim T., Abd El-Halim M., Baraka A.M., Morsy M.H. The protective Effect of Nigella Sativa Oil and The Derived Thymoquinone And Nigellone Against Thioacetamide Induced Liver Fibrosis In Rats. Bull. Alex. Fac. Med. 2005; 41(1): 75-82. 16. Madiha AH Hassan and Amal F Ketat. Sildenafil citrate increases myocardial cGMp content in rat heart, decreases its hypertrophic response to isoproterenol, loss of creatine kinase and troponin T. BMC Pharmacology 2005; 5(1): Full text Open access at http://www.springerlink.com/content/p7j6226941000102/ 17. Mohamed I El-Dakhakhny, Madiha A. Halim, Maged M. matta, safaa H. El-Rewini, Hoda M. Khalifa. Protection Against Acute Adriamycin-Induced Cardiotoxicity By Nigella Sativa Oil, Thymoquinone, Garlic Extract and CoQ10 In Rats. Bull. Alex. Fac. Med. 2005; 41(1): 47-60. 18. Madiha Abd El-Halim, Tarek Abd El-Azim, Samia M. Ali, Effect of Selective and Non-Selective Cyclooxygenase Inhibitors on Survival, Platelet Function and Vein Wall Inflammation in A Rat Model of Deep Vein Thrombosis. Bull. Alex. Fac. Med. 2006; 42 (1): 107-14. 19. Rida, Samia M. · Saudi, Manal N.S. · Youssef, Amal M. · Halim, Madiha A. Synthesis and Biological Evaluation of the Pyrazole Class of Cyclooxygenase- 2- Inhibitors. Letters in Organic Chemistry.2009 ;Vol. 6, No. 4., pp. 282-8. 20. Eman Abdelzaher, Ibtesam Abdel Reheem, Madiha Hassan, Aml Abd-El hameed, and Dalia Kamal, Effects of angiotensin converting enzyme inhibitors, peroxisome proliferators activated receptor -γ agonists, and statins on a rat model of hypertension. Bull. Alex. Fac. of Med. 2010;46(3): 231-45. Open access at http://www.ajol.info/index.php/bafm/article/viewFile/61897/49966 21. Adel A. Anglo, Madiha A. Hassan, Nagwa M Nour El Din, Hoda M Khalifa, Suzan A. Abdel Ghany. A possible role for gastroprotectives on Aspirin-induced gastric ulcer in rats. Bull. Alex. Fac. Med. 2010; 46 (1): 75-82. Open access at http://www.alexmed.edu.eg/journal/index.php/bulletin/article/viewFile/499/422
Azza Mohamed Ahmed Lotfy Baraka	1. Bekhit AA, Fahmy HT, Rostom SA, Baraka AM.Design and synthesis of some substituted 1H-pyrazolyl-thiazolo[4,5-d]pyrimidines as anti-inflammatory-antimicrobial Agents. Eur J Med Chem. 2003 Jan;38(1):27-36. 2. Bekhit AA, Baraka AM . Arch. Pharm. Pharm. Med. Chem. Arch. Pharm. Pharm. Med. Chem. 336, 111-118, 2003 3. Bekhit AA, Baraka AM. Novel milrinone analogs of pyridine-3-carbonitrile derivatives as promising cardiotonic agents..Eur J Med Chem. 2005 Dec;40(12):1405-13. 4. Bekhit A. A. and Baraka A. M. Synthesis and biological evaluation of some pyridine-3-carbonitrile derivatives as cardiotonic agents.., Boll. Chim. Farmac. 145, 3 (2005). 5. Adnan A. Bekhit and Azza M. Baraka. Synthesis and Biological Evaluation of Some Amino-Acid Derivatives as a Novel Class of Monoamine Oxidase-A Inhibitors, , Peptide Science, 195-196 (2006). 6. Adnan A. Bekhit, Hayam M. A. Ashour, Alaa El-Din A. Bekhit and Azza M. Baraka. Synthesis and biological evaluation of some novel pyrazole derivatives as anti-inflammatoryantimicrobial agents, , Drugs Fut., 32(Suppl. A): 38 (2007). 7. Guemei AA, El Din NM, Baraka AM, El Said Darwish I.Do desipramine [10,11-dihydro-5-[3-(methylamino) propyl]-5H-dibenz[b,f]azepinemonohydrochloride] and fluoxetine [N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-propan-1-amine] ameliorate the extent of colonic damage induced by acetic acid in rats? J Pharmacol Exp Ther. 2008 Dec;327(3):846-50. 8. Adnan A. Bekhit, Hayam M. A. Ashour, Yasser S. Abdel- Chany, Alaa El-Din A. Bekhit and Azza M. Baraka Synthesis and biological evaluation of some thaizolyl and thiadiazolyl derivatives of 1H-pyrazole as anti-inflammatory-antimicrobial agents, , Eur. J. Med. Chem. 43, 456-463 (2008) 9. Baraka AM, Ghoneim I. A New Naphthoquinone with Anti-inflammatory Activity from an Egyptian Collection of Echiochilonfruticosum.The Korean Society of Pharmacognosy .v.15, no.1, 2009, pp.22-26 10. Baraka A, ElGhotny S. Study of the effect of inhibiting galanin in Alzheimer’s disease induced in rats.Eur J Pharmacol. 2010 Sep 1;641(2-3):123-7. 11. Baraka AM, Guemei A Gawad HA. Role of modulation of vascular endothelial growth factor and tumor necrosis factor-alpha in gastric ulcer healing in diabetic rats. BiochemPharmacol. 2010 Jun 1;79(11):1634-9. 12. Baraka A, AbdelGawad H. Targeting apoptosis in the heart of streptozotocin-induced diabetic rats. J CardiovascPharmacolTher. 2010 Jun;15(2):175-81. 13. Baraka AM, Korish AA, Soliman GA, Kamal H. The possible role of estrogen and selective estrogen receptor modulators in a rat model of Parkinson’s disease. Life Sci. 2011 May 9;88(19-20):879-85. 14. Baraka AM, Deif MM. Role of activation of 5′-adenosine monophosphate-activated protein kinase in gastric ulcer healing in diabetic rats. Pharmacology. 2011;88(5-6):275-83. 15. Baraka AM, Ghoneim M. Role of heat shock protein in renal ischemic reperfusion injury in rats. African Journal of Pharmacy and Pharmacology Vol.5(18) , pp. 2050 – 2055 , November 2011. 16. Baraka AM, Hassab El Nabi W, El Ghotni S.Investigating the role of zinc in a rat model of epilepsy. CNS NeurosciTher. 2012 Apr;18(4):327-33. 17. Baraka A, El Ghotny S. Cardioprotective effect of renalase in 5/6 nephrectomized rats. J Cardiovasc PharmacolTher. 2012 Dec;17(4):412-6. 18. Baraka AM, Korayem H, Baraka M. Metformin as a potential therapeutic agent for osteoporosis in ovariectomized rats. ACTA ENDOCRINOLOGICA 2014; 10 (1), 31-40 19. AE Dief, ES Kamha, AM Baraka, AK Elshorbagy.Monosodium glutamate neurotoxicity increases beta amyloid in the rat hippocampus: a potential role for cyclic AMP protein kinase. NeuroToxicology 2014; 42, 76-82 20. AM Baraka, IE Darwish, MT Ghoneim, HKKorayem. β 2-adrenoceptor agonists as potential therapeutic drugs in diabetic peripheral neuropathy. European journal of pharmacology 2015; 746, 89-95 21. Baraka AM and Guemei A. Can Pharmacological Targeting of Advanced Glycation End Products Provide Protection Against Experimentally Induced Liver Fibrosis? Biochem Pharmacol (Los Angel) 2015, 4:2 22. O Nayel, M Sobhy, AM Baraka, M El Samak, CA Kader.The relevance of platelet glycoprotein GP IIb/IIIa polymorphism to anti-platelets response in acute coronary syndrome. European journal of clinical pharmacy: atención farmacéutica 19 (2), 83-92 23. M Ramadan, A Eltaweel, T El Nakhal, H Hemead, A Maraqa, D Abish, Baraka AM, Self-medication among Undergraduate Medical Students of Alexandria Faculty of Medicine: Where do We Stand? International Journal of Medical Students 2018; 6 (2), 52-55 24. Baraka AM , Abdel Gawad H, Yacout D, Baraka M. Pharmacological Activation of WNT- Β Catenin Signaling Pathway As A Potential Therapeutic Target In Osteoporosis Anatomy Physiology and Biochemistry 2018; 5 (3), 1-7 25. Passainte S. Hassaan; Abeer Dief, Ph.D; Teshreen Zeitoun; Azza M. Baraka; Robert M. J. Deacon; Amany Elshorbagy. Cortical tau burden and behavioural dysfunctions in mice exposed to monosodium glutamate in early life. Plos one 2019; 14 (8), e0220720 26. N Badae, N Zahran, A Baraka, R Elshinety, A Dief. Functional and morphological consequences after atorvastatin intake in a rat model of intracerebral haemorrhage. Bulletin of Egyptian Society for Physiological Sciences 2021; 40 (2), 86-102 27. Baraka AM, Hadidy W. ROLE OF AMBROXOL AS A PROPHYLACTIC AGENT AGAINST COVID-19. Pharmaceutical Research 2021; 6(1): 61-5. 28. CA Ismail, AM Baraka, RM Abdallah, OG El-Dien, DK Mostafa. Spergularia marina: a potential source of a novel calcium channel blocker with antihypertensive and diuretic activities. Eur Rev Med Pharmacol Sci. 2022; 26(2): 506-17.
Enas elSayed Darwish Hassan	1. Yasser H. Habib ,Mennatallah A. Gowayed , Sherien A. Abdel-hady ,Nevine M. El‐Deeb , Inas E. Darwish , Mahmoud M. El‐Mas. Modulation by antenatal therapies of cardiovascular and renal programming in male and female offspring of preeclamptic rats .Naunyn-Schmiedeberg’s Archives of Pharmacology (2021) 394:2273–2287 https://doi.org/10.1007/s00210-021-02146-7 2. Hossam A. N. Soliman1,2,3, Erik A. Toso 1, Inas E. Darwish3, Sa-mia M. Ali3 and Michael Kyba 1 ✉ .Antiapoptotic Protein FAIM2 is targeted by miR-3202, and DUX4 via TRIM21, leading to cell death and defective myogenesis .Received: 4 January 2021 Re-vised: 23 March 2022 Accepted: 30 March 2022. Springer na-ture.Official journal of CDD press. 29. Ahmed M. Farghaly 1,, Ola H. Rizk 1,2 , Inas Darwish 3,4, Manal Hamza 3, Mezna Saleh Altowyan 5 , Assem Barakat 6,7, and Mo-hamed Teleb 1,* .Design, Synthesis, Pharmacodynamic and In Sil-ico Pharmacokinetic Evaluation of Some Novel Biginelli-Derived Pyrimidines and Fused Pyrimidines as CalciumChannel Blockers .Molecules 2022.https://doi.org/10.3390/molecules27072240. Ashraf A Noah 1, Nesrine S El-Mezayen 2, Samar O El-Ganainy 3, Inas E Dar-wish 4, Elham A Afify 5.Reversal of fibrosis and portal hypertension by Em-pagliflozin treatment of CCl4-induced liver fibrosis: emphasis on Gal-1/NRP-1/TGF-β and Gal-1/NRP-1/VEGFR2 pathways. EUROPEAN JOURNAL OF PHARMACOLOGY. Eur J Pharmacol2023 Nov 15:959:176066. doi: 10.1016/j.ejphar.2023.176066.Epub 2023 Sep 27.
Omnia Anwar Mohamed Attia	سيتاجليبتين يضعف شفاء قرحة المعدة المستحدثة تجريبيا عن طريق تثبيط iNOS و COX-2 مقارنة آثار إسسيتالوترام وأتورفاستاتين على تصلب الشرايين المستحدث عن طريق تغيير النظام الغذائي في الفئران عزل السلالات البكتيرية المقاومة للجرام السلبي من وحدات العناية المركزة لحديثي الولادة في مدينة تبوك وحساسيتها لبعض المستخلصات النباتية الطبية. مقارنة آثار سيتاغليبتين والاستروجين على استحداث هشاشة العظام عن طريق استئصال المبيضين في الفئران مستخلص التوت الاساي يخفف من الفشل الكلوي الحاد الناجم عن حقن الجلسرين في الفئران دراسة النشاط المضاد للميكروبات لبذور حبة البركة الميثانولية ومستخلصات جذور سوسوريا لابا على البكتيريا سالبة الجرام المقاومة للأدوية المتعددة دراسة مقارنه ما بين كفاءة التعلم القائم على المشاكل والتعلم القائم على اشتراك الفريق بين طلاب التمريض للدراسات العليا في جامعة رأس الخيمة الطبية والعلوم الصحية: دراسة مقطعية مستخلص حبوب البن الأخضر يخفف السمية الكلوية الحادة في الفئران الناتجة عن حقن الجنتاميسين السيتاجلبتين يضعف شفاء قرحة المعدة المستحثة تجريبيا من خلال تثبيط iNOS وCOX2
Wafaa Ahmed Ismail Howidy	1. Inas E. Darwish, Alia M. Arab, Tarek A. Azeim, Teshreen M. Zeitoun, Wafaa A. Is Curcumine Effect Comparable to 5- Aminosalicylic Acid or Budesonide on a Rat Model of Ulcerative Colitis Induced by Trinitrobenzene Sulfonic Acid? International Scholarly and Scientific Research & Innovation 2013; 7(8). 2. Wafaa Hewedy, Wessam El-Hadidy. Neuroprotective effect of renin angiotensin system blockers on experimentally induced Alzheimer’s disease in rats. Int J Basic Clin Pharmacol. 2015; 4:853-859. 3. Mohamed G. Elsakkar, Maha M. Eissa, Wafaa A. Hewedy, Rasha M. Nassra, Soha F. Elatrebi. Sodium valproate, a histone deacetylase inhibitor, with praziquantel Page 3 of 6 ameliorates Schistosoma mansoni-induced liver fibrosis in mice. Life Sciences 2016; 162:95–101. 4. Wafaa A. Hewedy, Dalia K. Mostafa. Nebivolol suppresses asymmetric dimethylarginine and attenuates cyclosporine-induced nephrotoxicity and endothelial dysfunction in rats. Pharmacological Reports; 2016; 68(6): 1319–1325. 5. Samia Mohamed Ali, Amr Abdel Kader Okda, Iman Samy Dessouky, Wafaa Ahmed Hewedy, Noha Mahmoud Zahran, Butheina Abdul-wally Alamrani. L-Carnitine ameliorates knee lesions in mono-iodoacetate induced osteoarthritis in rats. Alexandria Journal of Medicine 2017; 53(1), 61–66. 6. Wafaa A. Hewedy. Linagliptin attenuates chronic post-ischemia pain: Possible anti- inflammatory and anti-oxidant mechanisms. European Journal of Pharmacology 2018; (828):110–118. 7. Wafaa A. Hewedy. Effect of Boswellia serrata on rat trachea contractility in vitro. The Natural Products Journal 2019; 9: 1-11. 8. Hazem F. Mannaa, Tarek A. Abd Allah, Wafaa A. Hewedy, Eiman I. Zaki, Salma H. Kandiel2 Linagliptin ameliorates hepatic derangement and endothelial dysfunction in type 2 diabetic rats: biochemical, functional and histo-morphometric analysis. European Journal of Pharmaceutical and Medical Research 2019; 6(7): 87-102. 9. Samia Ali, Yehia Ghanem, Ola Sharaki, Wafaa Hewedy, Esraa Habiba. The Impact of Different Regimens of Vitamin D3 on Glucose Homeostasis in Type 2 Diabetic Patients. Asian J Pharm Clin Res 2019;12(12):21-6. 10. Salma Hany Kandiel, Tarek Abd El-Azim Abd Allah, Wafaa Ahmed Hewedy, Hazem Farag Mannaa, Eiman Ibrahim Zaki. Comparative histological study of the potential protective effect of Acarbose, Linagliptin and Quercetin on the aorta of type 2 diabetic rat. Egyptian Journal of Histology. DOI: 10.21608/EJH.2021.63762.1434 11. Wafaa A. Hewedy. Effects of treatment with sitagliptin on hepatotoxicity induced by acetaminophen in mice. Brazilian journal of pharmaceutical sciences 2020; 56: e18482
Amany Ali Khalil Nawar	• Hanaa Aboelkasem Alazrag, Mervat Eid Abdelghaffar, Huda Mahmoud Khalifa, Rasha Mohamed Adel Nassra, Amany Ali Khalil Nawar. The Role Of Lingo-1 and Myelin Basic Protein MRNAS In Central Remyelination In Ethidium Bromide-Induced Demyelination In Rats- Asian Journal of Pharmaceutical and Clinical Research • September 2019 • Amany Ali Nawar, Nancy Mohamed El Sekily. Promising effect of dapagliflozin on ovariectomized rat model of osteoporosis. International Journal of Anatomy and Research, Int J Anat Res 2020, Vol 8(3.3):7728-37. ISSN 2321-4287 • Elsayed Metwally, Amany Nawar. The possible Effect of Trimetazidine and Sitagliptin on Chronic Model of Arthritis in Male Albino rats; Histomorphometric study. 2021, Egyptian Journal of Histology DOI:10.21608/ejh.2021.37139.1334
Dalia Yaqoot Mohmed Yaqoot	An eye drop combination for the treatment of Staphylococcus aureus induced keratitis in rats. Antenatally administered NSAIDs improve renal cyclooxygenase and MAPK cascade in rats with preeclampsia. Gestational NSAIDs distinctly reprogram cardiac injury in preeclamptic rats: roles of cyclooxygenase,apoptotic and autophagic trails. Montelukast potentiates the anti-inflammatory effect of NSAIDs in the rat paw formalin model and simultaneously minimizes the risk of gastric damage. Antibacterial activity of clove oil-loaded nanoformulation against burn wound infection. Antibacterial activity of Jojoba and Citrullus Colocynthis oils in staphylococcus wound infection induced in mice. Pharmacological activation of WNT-B Catenin signaling pathway as a potential therapeutic target in osteoporosis . The suppression of MAOK/NOX/MMP signaling prompts renoprotection conferred by prenatal naproxen in weaning preeclamptic rats.

Workshops

workshop	date
التقنيات الأساسية في زراعة الخلايا وأبحاث الخلايا الجذعية	Apr-14
حرق الجرح من الأساسيات إلى الإدارة	Apr-14
ضمان الجودة والاعتماد: طرق تقييم الطلاب	Apr-13
ورشة عمل الإسكندرية للمنظار الداخلي وطب الجهاز الهضمي	Oct-17
ABC kids	2023
تشريح الدماغ والتنميط السلوكي والتصوير التجسيمي	January4th-5th, 2022
basic understanding,methodologies and research applications in CERRMA

Training

Community or Organization

جوائز

Community or Organization

جوائز

أسم الجهاز	research techniques
Powerlab with labschart Pro & brigde amplifier	Allow for measuremnt of many parameter in rodenets acccording to the attached acessories below
Pressure transduce	measurement of isometri contraction of isolated organs
Organ bath	measurement of isometri contraction of isolated organs
Non invasive BP transducer	Non invasive Measurment of BP in rats
Spirometry	measurment of respiratory functions in rodents
bioamplifier and ECG electrodes	ECG recording
Oximeter	measurment of O2 saturation
Flowmeter and US flow probe	measurement of blood flow in a single vessel in rats or mice
Polygraph	recording of isotonic or isometric tension changes
pressure transduced	invasive blood pressure measurment
isometric pressure transdcuer	measurment of isometric contraction of isolated organs
Steriotaxis	allows for local injection in different areas of the brain of rats and mice
spectrophotometer	measurment of color absorbance of solution at specific wave length
sppectrflorometer	measurment of flouresence of solutions
Analytical balance	accurate weighing (gm-mg)
Homogenizer 4000pm	tissue homogenization
ElISA Reader	meaurement ELISA kits
Shaker	meaurement ELISA kits
Washer	meaurement ELISA kits
Centrifuge	centrifugation
Lab incubator	routine incubator (37-60º C)
Oven	heating, sterilization
Pipette man starter kit	Measurement

training	date
التدقيق السريري	7/11/2023

satff members	name of commite or organisation or journal
Khamis ahmed mahmoud gomaa	AAAAI (USA)membership for more than 25years. EACI( EUROPE ) for more than 20 years.French Society of allergy & clinical immunology since 1982. Head of society of allergy &immunology & COPD ( EGYPT )more than 20 years. Egalitarian Society of Allergy & Clinical Immunology .

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